Azadeh Mohebbi; Rezvan Amiri; Nasim Nejadsajadi; Maryam Khalili; Saman Mohammadi; Abnoos Mokhtari; Mahin Aflatoonian; Zahra Rahnama
Abstract
Background: The association of cherry angioma with metabolic syndrome and fatty liver has been proposed in a few studies. This study evaluated the prevalence of cherry angiomas in patients with type II diabetes mellitus compared with healthy adults.Methods: This cross-sectional study was conducted on ...
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Background: The association of cherry angioma with metabolic syndrome and fatty liver has been proposed in a few studies. This study evaluated the prevalence of cherry angiomas in patients with type II diabetes mellitus compared with healthy adults.Methods: This cross-sectional study was conducted on 100 patients with type II diabetes mellitus and 100 age and sex-matched healthy adults. Demographic features of the participants and the location and number of the lesions were recorded. Data were analyzed by SPSS 16. Mean ± standard deviation and frequency were used for quantitative analysis. The chi-squared test and independent t-test were utilized to evaluate the association of qualitative and quantitative data with the number of cherry angiomas, respectively.Results: Cherry angiomas were more prevalent in the diabetes group (47%) than in controls (30%) (P = 0.013). Lesions in diabetic patients were more prevalent in females than males (P = 0.042). Furthermore, the number of lesions in the diabetes group significantly increased parallel to aging (P = 0.004).Conclusion: In the present study, significantly more cherry angiomas were observed in patients with type II diabetes mellitus than in healthy controls. Furthermore, the number of lesions was higher in females and elderly subjects in the diabetes group.
Saman Mohammadi; Maryam Khalili; Mahin Aflatoonian; Rezvan Amiri; Zahra Sharif; Saeedeh Farajzadeh; Azadeh Mohebbi
Abstract
Background: Atopic dermatitis is a chronic relapsing inflammatoryskin disease that has possible associations with other diseases suchas allergic conditions, autoimmune skin diseases, and systemicdiseases. We evaluated the prevalence of alopecia areata andthyroid autoimmunity in children with atopic dermatitis.Methods: ...
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Background: Atopic dermatitis is a chronic relapsing inflammatoryskin disease that has possible associations with other diseases suchas allergic conditions, autoimmune skin diseases, and systemicdiseases. We evaluated the prevalence of alopecia areata andthyroid autoimmunity in children with atopic dermatitis.Methods: This was a cross-sectional study on 124 children(62 children with atopic dermatitis and 62 healthy children).Demographic features of the participants and duration of diseasein children with atopic dermatitis were recorded. Antithyroidperoxidase and thyroid stimulating hormone were evaluated inboth groups. Odds ratio (OR) and 95% confidence interval (CI)were calculated to estimate relative risk. The chi-squared testand analysis of variance test (ANOVA) were used to evaluatethe association of thyroid autoimmunity with the demographicand clinical features of patients.Results: Thyroid autoimmunity was only detected in atopicdermatitis children and not in the control group, and the differencewas statistically significant [OR = 4.32, 95% CI = 2.15–10.81,P = 0.04). Furthermore, overt thyroid disease was significantlymore common in the atopic dermatitis group compared withthe control group (OR = 4.46, 95% CI = 1.15–17.24, P = 0.03). Apersonal history of alopecia areata was also significantly morecommon in the atopic dermatitis group (OR = 4.46, CI = 1.17–15.29,P = 0.030). In addition, there was no significant difference betweenthyroid autoimmunity and overt thyroid disease in the patients’severity of atopic dermatitis and demographic features (P > 0.05).Conclusion: Patients with atopic dermatitis had a significantlyhigher percentage of thyroid autoimmunity, overt thyroid disease,and alopecia areata than the control group.